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Statins for Fibroids?

New research suggests that statin drugs commonly prescribed to lower high cholesterol levels may do double duty in women with benign fibroid tumors of the uterus. Fibroids, the most common tumors in the female reproductive system, account for half the annual hysterectomies in the U.S. Earlier research has shown that statins have anti-tumor effects on breast, ovarian, prostate, and lung cancers, but until recently, their effect on fibroids was unknown, researchers from the University of Texas Medical Branch at Galveston said. They collaborated on the investigation with teams from Baylor College of Medicine, the Georgia Regents University and the University of Texas Health Science Center at Houston. Their study in laboratory tissue cultures showed that the statin simvastatin blocks the growth of fibroid tumor cells and also promotes calcium-dependent cell death mechanisms in the tumor cells themselves. More research is needed before we know whether or not treatment with statins can elicit positive effects in fibroid tumors in women, but studies in animals are currently underway.